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In the rapidly evolving landscape of precision science, Gene Copy Number Analysis (CNA) has emerged as a critical tool powering innovation across sectors—from agricultural biotech to advanced pharmaceuticals. By accurately quantifying the number of copies of specific genes, CNA provides vital insights that can accelerate research, improve product development, and guide clinical decision-making.
Yet, while the value of CNA is clear, the execution is often technically demanding. That’s where outsourcing to specialists like AttoDNA becomes a game-changer.
CNA measures variations in the number of copies of a particular gene, which can influence everything from disease risk and drug response to crop resilience and trait heritability. These variations—known as copy number variations (CNVs)—can have profound biological effects and are increasingly recognised as key markers in both clinical and research settings.
In agriculture, CNA helps validate transgene insertions and track inheritance patterns across generations. For example, a seed company engineering drought-resistant maize might use CNA to confirm that the drought-tolerance gene is present in the desired copy number before commercial rollout.
By providing rapid, reproducible results, CNA allows breeders to streamline selection and shorten breeding cycles, getting improved varieties into fields faster.
In drug development, CNA plays a pivotal role in biomarker discovery and precision medicine. Take HER2-positive breast cancer, for instance—patients with increased HER2 gene copies benefit from targeted therapies like trastuzumab. Without CNA data, these patients might not be correctly identified.
Pharmaceutical companies also use CNA to monitor gene dosage effects in clinical trials, ensuring that new therapies are both safe and effective in populations with relevant genetic profiles.
For geneticists studying inherited disorders or tumour progression, CNA offers a powerful lens. Imagine a university research team exploring autism spectrum disorders. They may find that certain CNVs affecting neuronal development genes are more frequent in affected individuals.
With AttoDNA’s support, such teams can focus on interpretation rather than technical hurdles—moving closer to breakthroughs in understanding complex genetic traits.
Conducting accurate CNA requires advanced platforms, rigorous validation, and highly trained personnel. Many labs lack the resources to maintain this in-house without significant investment. That’s why AttoDNA offers a reliable outsourcing option, providing:
A European agritech firm recently partnered with AttoDNA to support a breeding programme targeting protein content in soybeans. Through rapid CNA validation, the team was able to confirm transgene presence across hundreds of samples in a fraction of the time it would have taken using internal resources. The result? A full season of field trials saved—and a leg up in the race to commercialisation.
Whether you're validating a cancer biomarker, refining a new pharmaceutical compound, or advancing crop traits in the field, AttoDNA delivers reliable, actionable CNA insights—fast.
Connect with our specialists today at www.attodna.com to explore how outsourcing your CNA can power your next breakthrough.